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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAT1A
All Species:
49.39
Human Site:
Y92
Identified Species:
72.44
UniProt:
Q00266
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q00266
NP_000420.1
395
43648
Y92
D
T
I
K
H
I
G
Y
D
D
S
A
K
G
F
Chimpanzee
Pan troglodytes
XP_515585
413
45605
Y92
E
A
V
K
H
I
G
Y
D
D
S
S
K
G
F
Rhesus Macaque
Macaca mulatta
XP_001087977
396
43707
Y93
D
T
I
K
H
I
G
Y
D
D
S
A
K
G
F
Dog
Lupus familis
XP_851933
396
43499
Y93
G
A
I
R
H
I
G
Y
D
D
S
A
K
G
F
Cat
Felis silvestris
Mouse
Mus musculus
Q91X83
396
43490
Y93
D
T
I
K
H
I
G
Y
D
D
S
A
K
G
F
Rat
Rattus norvegicus
P13444
397
43679
Y93
D
T
I
K
H
I
G
Y
D
D
S
A
K
G
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421512
396
43734
Y93
D
A
I
R
H
I
G
Y
D
D
S
A
K
G
F
Frog
Xenopus laevis
NP_001080175
396
43767
Y93
D
T
I
K
Y
I
G
Y
D
D
S
S
K
G
F
Zebra Danio
Brachydanio rerio
NP_956165
390
43271
Y87
D
T
I
K
H
I
G
Y
D
N
S
E
K
G
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40320
408
44678
Y103
E
T
V
Q
H
I
G
Y
D
D
S
S
K
G
F
Honey Bee
Apis mellifera
XP_623669
404
44652
Y100
D
T
V
K
H
I
G
Y
D
D
S
S
K
G
F
Nematode Worm
Caenorhab. elegans
P50305
404
44016
Y89
D
S
S
K
G
F
D
Y
K
T
C
N
V
L
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
A9P822
392
43195
K89
D
V
G
L
D
A
D
K
C
K
V
L
V
N
I
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LUT2
393
42777
N89
D
V
G
L
D
A
D
N
C
K
V
L
V
N
I
Baker's Yeast
Sacchar. cerevisiae
P10659
382
41800
T90
A
K
G
F
D
Y
K
T
C
N
V
L
V
A
I
Red Bread Mold
Neurospora crassa
P48466
395
42967
Y91
N
A
I
K
D
I
G
Y
D
D
S
S
K
G
F
Conservation
Percent
Protein Identity:
100
80.1
98.2
95.9
N.A.
96.2
95.7
N.A.
N.A.
90.9
84.8
82.2
N.A.
68.6
70.5
68.3
N.A.
Protein Similarity:
100
88.6
99.2
98.4
N.A.
98.4
98.4
N.A.
N.A.
96.4
92.9
92.6
N.A.
85.5
86.3
83.1
N.A.
P-Site Identity:
100
73.3
100
80
N.A.
100
100
N.A.
N.A.
86.6
86.6
86.6
N.A.
73.3
86.6
20
N.A.
P-Site Similarity:
100
93.3
100
86.6
N.A.
100
100
N.A.
N.A.
93.3
100
93.3
N.A.
100
100
26.6
N.A.
Percent
Protein Identity:
61
N.A.
N.A.
60.7
66.5
68.1
Protein Similarity:
75.9
N.A.
N.A.
77.4
81.2
82.7
P-Site Identity:
6.6
N.A.
N.A.
6.6
0
73.3
P-Site Similarity:
6.6
N.A.
N.A.
6.6
6.6
86.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
25
0
0
0
13
0
0
0
0
0
38
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
19
0
7
0
0
0
0
% C
% Asp:
69
0
0
0
25
0
19
0
75
69
0
0
0
0
0
% D
% Glu:
13
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% E
% Phe:
0
0
0
7
0
7
0
0
0
0
0
0
0
0
75
% F
% Gly:
7
0
19
0
7
0
75
0
0
0
0
0
0
75
0
% G
% His:
0
0
0
0
63
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
57
0
0
75
0
0
0
0
0
0
0
0
19
% I
% Lys:
0
7
0
63
0
0
7
7
7
13
0
0
75
0
0
% K
% Leu:
0
0
0
13
0
0
0
0
0
0
0
19
0
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
0
0
0
0
0
7
0
13
0
7
0
13
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
7
7
0
0
0
0
0
0
0
75
32
0
0
0
% S
% Thr:
0
50
0
0
0
0
0
7
0
7
0
0
0
0
0
% T
% Val:
0
13
19
0
0
0
0
0
0
0
19
0
25
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
7
0
82
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _